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Under conditions of oxidative stress and in the presence of retinoic acid, mammalian TGR was recently shown to bind the retinoic acid receptor, presumably to stabilize the receptor and allow its continued signaling activity [12]

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In the compartmentalization experiments, SOD1 was separated from the cells cultured in a 24-well plate using a tightly fit dialysis insert equipped with a 3.5-kDa cutoff membrane (Thermo Fisher Scientific, UK)