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5.1 Comprehensive strategy combining multiple medication classes A recent actuarial modeling study assessed the potential clinical benefits of combining three major pharmacologic classes—SGLT2 inhibitors, GLP-1 receptor agonists, and the non-steroidal MRA finerenone—using data from large-scale randomized trials (161)

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Oral and topical glutathione are gentler routes, though their effects are modest and gradual

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