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90,91 Women with fibromyalgia were reported to be at nearly four times higher risk of metabolic syndrome than healthy women, and co-occurrence was correlated with increased fibromyalgia severity in a study with 138 participants

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Key Preclinical Study (Neelakantan et al., 2018): Treatment in diet-induced obese mice produced progressive body weight loss, reduced white adipose tissue mass and adipocyte size, decreased total cholesterol, and no changes in food intake — effects were metabolic, not appetite-driven