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Among the main neurotransmitters that are active in sleep are gamma-aminobutyric acid (GABA), serotonin, and norepinephrine (both a neurotransmitter and a hormone)

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Furthermore, decreased intracellular calcium levels resulted in a reduced production of receptor interacting protein (RIP) 2/caspase-1, which suppressed the phosphorylation of IκBα and activation of NF-κB by about 50%