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NADPH-mediated support of metastasis is associated with the oxidative pentose phosphate pathway (oxPPP), which plays a key role in redox status and various aspects related to cancer cell viability

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This triple agonist design, developed by Eli Lilly under the research code LY3437943, represents a fundamentally different approach from semaglutide (which targets only GLP-1) or tirzepatide (which targets GLP-1 and GIP)