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A similar pattern of OR estimates were observed (1.09, 1.07, 1.06) for different levels of daily vitamin A intake at 200 μg (Supplementary Table 2

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However, the SAPNets are based on understandable descriptors (e.g., size, shape, aspect-ratio, and type of coating) and do not require additional computational calculations, allows consideration in environmental influence (such as solvent and pH), and the users can easily see how the change of the descriptor values will influence the predicted toxicity