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For example, cytotoxic T lymphocyte-associated antigen 4 (CTLA-4)-blocking peptides, such as specific peptide fragments derived from ipilimumab, enhance CD8+ T cell activation by inhibiting CTLA-4-mediated immune suppression [141]

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Furthermore, in our study, the anti-apoptotic BCL2 expression was downregulated with WGM extracts at both concentrations and this could be due to the presence of anti-cancer compounds such as apigenin