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Keywords: nose to brain delivery system, lipid based nanoparticle, in situ gel, bypassing BBB Introduction Global healthcare data indicate a significant increase in the prevalence of central nervous system (CNS) diseases, which contribute approximately 6–8% to the global economy

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[DOI] [PubMed] [Google Scholar] 182.Yant L.J., Ran Q., Rao L., Van Remmen H., Shibatani T., Belter J.G., Motta L., Richardson A., Prolla T.A