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The Mitochondrial Transcription Factor TFAM in Neurodegeneration: Emerging Evidence and Mechanisms

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Further, significant elevation of Cys106-oxidized DJ-1 has been reported in erythrocytes of untreated PD patients [370], and more acidic isoforms of DJ-1 have been detected in extracts of frontal cortex from patients with sporadic PD compared to control subjects [371]