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KPV is the only component that, despite its alpha-MSH origin, is not melanocortin-receptor-mediated, which distinguishes it from complete alpha-MSH and melanotan analogs

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A prominent line of reasoning about the pathogenesis of schizophrenia, for instance, is that the schizophrenic brain is constitutively vulnerable to oxidative insults and that typically benign oxidative challenges can cause changes to the schizophrenic brain that manifest as symptoms [45]