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Frontiers | Effects of fucoidan on growth performance, immunity, antioxidant ability, digestive enzyme activity, and hepatic morphology in juvenile common carp (Cyprinus carpio)

Previous preclinical and clinical studies reported that IL-7 treatment increased T cell counts, but its effect on peripheral blood T cells in cancer patients and molecular mechanisms have not been explored.METHODS We investigated effects of long-acting recombinant human IL-7 conjugated to a hybrid IgD/IgG4 Fc domain (rhIL-7-hyFc) on peripheral T cells in patients with advanced solid tumors

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For example, Vupanorsen, an ASO drug that inhibits the synthesis of Angiopoietin-like 3 (ANGPTL3) protein, demonstrated a notable reduction in non-HDL cholesterol levels in patients with dyslipidemia under statin treatment [246]