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Furthermore, lycopene reduced the activity of acetyl-CoA carboxylase, sterol regulatory element binding protein 1 (SREBF1), fatty acid synthase, microsomal triglyceride transfer protein (MTP), Niemann-Pick C1Like1 ( NPC1L1 ), cholesterol O -acyltransferase (ACAT) 2 ( ACAT2 ), Which lycopene also reduced the mRNA expression levels of SREBP1c , LXRα , ACLY , FABP1 , FABP10 and FATP4

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