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Inject slowly into the peptide vial: Direct the stream of liquid gently down the inside wall of the vial rather than directly onto the lyophilised powder, to minimise foaming and potential denaturation

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The studies were done on rodents, the b12 isn’t available in the kidneys for very long, weeks, not months it seems.and whether humans with b12 deficiency because of a broken system can access this b12 we won’t know without further research