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This is further supported by the study of Yang, Huang (102) in which the significant induction of cytokines, chemokines, and adhesion molecules (such as TNF-α, IL-1β, MCP-1, CXCL1, ICAM-1, VCAM-1) in human brain microvascular endothelial cells by SARS-CoV-2, suggesting an activation of the vascular endothelium in the brain

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