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As mTORC1 regulates ATF4 translation through a mechanism requiring its 5’-UTR (Ben-Sahra et al., 2016

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252 The NICD then translocates into the nucleus, where it forms a transcriptional complex with RBP-Jκ and Mastermind-like (MAML) coactivators, activating downstream targets such as Hes, Hey, c-Myc, and Bcl-2