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Autophagy, Metabolic, and Other Emerging Pathways Several peptides act through less conventional mechanisms, including regulation of autophagy, activation of metabolic receptors, and other mechanisms that remain to be fully elucidated (Figure 3E)

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Mice (N = 3 per group) were given daily intraperitoneal injections of ALA at 50 mg/kg (group 1), 30 mg/kg (group 2), or 20 mg/kg (group 3), or the combination of ALA 30 mg/kg + Asc 4 g/kg (group 4), and ALA 20 mg/kg + Asc 4 g/kg (group 5)