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We also quantified sCD14, a nonspecific monocyte activation marker, levels in the plasma of our study participants, which showed a significant elevation in LC patients compared to the HC and R groups ( Figure 6J )

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The participation of ThDP in cellular folate absorption (Figure 2A) endows SLC44A4 with a physiologically relevant function to return ThDP that is extruded in exchange for folate, back to the cell (Figure 2A)