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[19] As a result, the FDA has notified healthcare professionals that the Warnings and Precautions section of the labels for the 5-ARI class of drugs has been revised to include new safety information about the increased risk of being diagnosed with these rare but more serious forms of prostate cancer

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Treatment targets Clinical targets of therapy (statement #14: grade of recommendation D) For early diagnosed patients , treatment can realistically aim to prevent all the complications of CBS deficiency , whilst maintaining normal growth and nutrition and allowing the patient normal opportunities for employment and family life