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Diabetic Wound Healing Diabetic wound healing studies in rats using collagen dressings with GHK demonstrated higher glutathione and ascorbic acid levels, better epithelialization, 9-fold increased collagen synthesis in healthy rats, and activation of fibroblasts and mast cells

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Further study with IL-1β-induced mouse primary chondrocytes demonstrated that this effect was achieved by suppressing the p38 MAPK signaling pathway (Li et al