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Signs And Symptoms Of Vitamin B12 Deficiency Anaemia (lack of red blood cells) Symptoms of anaemia include: Fatigue, dizziness, paleness, and a rapid heart rate Neuropathy (damage to the nerves) Symptoms of neuropathy include balance problems, weakness, numbness, and tingling

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Folic acid is essential for a fetus to develop normally, and methotrexate interferes with the body’s ability to break down and use folic acid