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33 Our study shares high similarity with previous studies in reduced microbiota diversity, gut-brain axis action and elevated inflammatory markers, but differ in changes in specific strains and the focus of metabolic pathways

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Verma reports holding a Tier 1 Canada Research Chair in Cardiovascular Surgery and receiving grants, research support, and speaking honoraria from and acting as an advisor for Amgen, AstraZeneca, Bayer, Boehringer Ingelheim, the Canadian Heart Research Centre, the Canadian Medical and Surgical Knowledge Translation Research Group, Eli Lilly, HLS Therapeutics, Humber River Health, Janssen, Merck, Novartis, Novo Nordisk, Pfizer, PhaseBio, S & L Solutions Event Management, Inc, Sanofi, and Sun Pharma