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10 The HAS recommended that DPD deficiency be tested by determining plasma uracil concentrations in patients with planned fluoropyrimidine treatment, “as it is considered to be the most likely to be able to identify at least, and as far as possible, all patients with complete DPD deficiency.” 10,33 As a consequence, the plasma uracil test was standardized across French laboratories, and thresholds for deficiency and treatment decisions were developed

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