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This decrease in autophagy, particularly lipophagy, resulted in the buildup of LDs, and the resulting large lipid depots exacerbated the situation by further impeding the autophagic process, favouring a path for the metabolic syndrome of ageing via a potential feedback loop

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[DOI] [PubMed] [Google Scholar] 79.Saqib U., Kelley T.T., Panguluri S.K., Liu D., Savai R., Baig M.S., Schürer S.C

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