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10.5603/GP.2016.0095 [DOI] [PubMed] [Google Scholar] 29.Anisimov VN, Khavinson VK, Provinciali M, Alimova IN, Baturin DA, Popovich IG, Zabezhinski MA, Imyanitov EN, Mancini R, Franceschi C

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Resveratrol Activate Genes That Promote Resilience Against Stress (AKA Stress Response/Longevity Genes) Plants produce phytochemicals (like resveratrol) under stress These compounds either attract pollinators or in some cases, deter insects In humans, phytochemicals activate a variety of stress response pathways, resulting in many beneficial effects such as: The activation of SIRT1, which is linked to anti-inflammatory activity, metabolic adaptations, and neurological protection The activation AMP-kinase, a fuel-sensing enzyme that inhibits mTOR, leading to the down-regulation of cellular growth pathways Resveratrol and Exercise 250 mg/day of resveratrol blunted the positive effects of exercise in elderly men (aged 60-72) who exercised by engaging in cycling and CrossFit 3x/week for 8 weeks (Study) Which positive effects