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Particularly for organic nanocarriers, the precise tuning of hydrophilic–hydrophobic ratios fundamentally governs not only nanomedicine stability and aqueous dispersibility but also determines drug release mechanisms and in vivo biodistribution patterns [108]

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Topical melatonin 0.1% is of interest because it may help support the hair growth cycle, provide antioxidant support around the follicle, and contribute to a healthier scalp environment