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(1971) reported the occurrence of renal adenocarcinomas in 4 out of 26 male Fischer rats exposed to AFG1 via gavage, while this tumour was not reported for the animals exposed to AFB1

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Their argument is based on the hypothesis proposed by Pickup & Crook [5] which suggest that long-term innate immune system activation, resulting in chronic inflammation brings about a disease instead of repair, potentially resulting in the development of type 2 diabetes