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Under the circumstance of endothelial injury, platelets will firstly adhere to the exposed subendothelial matrix with the help of von Willebrand factor (vWF) [44] and become activated when they interact with collagen [45]

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It sits in the membranes of keratinocytes and fibroblasts (the two main cell types responsible for skin structure and barrier function), and it pulls ergothioneine in from both the bloodstream and, when applied topically, from the surface