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Major thiol- (A) and non-thiol compounds (B) involved in the... | Download Scientific Diagram

doi: 10.1128/IAI.00059-09 [DOI] [PMC free article] [PubMed] [Google Scholar] 111

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Succination of GSDMD prevents its interaction with caspase-1 that liberates the N -terminal domain of GSDMD (GSDMD-N), which is the active form amenable to oligomerization and formation of pores in the plasma membrane