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Physiologically, patients with asthma frequently experience disruptions in their melatonin levels, namely a delayed acrophase in peak serum concentrations, as well as in the amount of GSH produced in the lung ( In clinical practice, melatonin is often prescribed at a dose of 2mg for the average (70kg) human adult ( In summary, our findings identify melatonin as a regulator of ILC2 effector function through a glutathione-dependent, receptor-independent pathway

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