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10.1083/jcb.111.6.2319 [DOI] [PMC free article] [PubMed] [Google Scholar] Robinson, M.S

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Fe 2+ formed by intestinal absorption or erythrocyte degradation can be oxidized by ceruloplasmin to Fe 3+ , which binds to transferrin (TF) on the cell membrane to form TF-Fe 3+ , which forms a complex through membrane protein TF receptor 1 (TFR1) to endocytose this complex 23