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The mechanism is that high temperatures and inflammatory factors can activate the P38-mitogen-activated protein kinase (MAPK) signaling pathway, and the expression levels of apoptosis signal-regulating kinase 1 (ASK1) and MAPK-activated protein kinase 2 (MK2) proteins are significantly up-regulated, which can be inhibited by L-theanine

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Gradually increase to twice daily if your skin tolerates it well