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Because of their various physiological functions in viral infection and inflammation, the use of N-acetylcysteine (NAC) and sodium thiosulfate (STS) [1, 2] was recommended in the very early stages of the pandemic, by the authors and various other scientists, for both prevention and treatment of COVID-19

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It was found that MnO 2 nanoparticles obviously degraded MB in the presence of GSH (Figure 1B, Supplementary Figures S2, S3), which was attributed to the GSH-responsive Mn 2+ release from MnO 2 to initiate the ROS generation