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Importantly, true capillaries are responsible for the uptake of nutrients, oxygen, and water and the efflux of metabolic waste [139,140,141], while post-capillary venules with their perivascular space(s) (PVSs) serve as a conduit for interstitial metabolic waste disposal via the PVS or glymphatic system

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Transcriptome sequencing of esr1-1 revealed altered expression of several genes involved in responses to biotic and abiotic stresses and hormone signaling pathways (Thatcher et al., 2015)