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4.4 Data analysis and visualization The reads were processed using a Divisive Amplicon Denoising Algorithm (DADA) 2-based pipeline conducted within the QIIME2 22.2 platform ( To determine the differentially abundant taxa across body habitats, we conducted ANCOM-BC, which estimates the unknown sampling fractions and corrects the bias induced by their differences through a log-linear regression model (Kanehisa and Goto, 2000

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More specifically, this change may be related to increased Hb oxidation and, as a consequence, metHb production