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doi: 10.1007/s00604-020-04468-4

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Beyond vitamin E, nutritional interventions with ω-3 PUFAs have shown clinical relevance for AD prevention: long-term ω-3 PUFA intake in middle-aged adults lowers cerebrospinal 4-HNE levels and reduces preclinical AD risk, providing scientific rationale for nutrition-based primary prevention strategies targeting ferroptosis (247)