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Here we report that these two oncogenic pathways may not act in concert, but act apparently partially antagonistic at least in human GIC models, potentially accounting for disappointing results with inhibition of either pathway in the clinic 29,30,31 , but also providing new concepts on how to modulate these pathways more efficiently to improve the outcome of glioblastoma

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You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for “MHRA yellowcard” in the Google Play or Apple App Store