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Although several studies have demonstrated the efficacy of RSL3 in various animal models ( in vivo ( To date, the majority of studies regarding drug-tolerant persister cells have focused on persister cells from immortalized cell lines, demonstrating that they occur as a small subset of the total tumor population ( In summary, we studied the characteristics of CRC DTP cells derived from the chemotherapy or targeted agents, and the effects of ferroptosis on persister cells

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