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A decline in SCFA-producing taxa, such as those from the genera Prevotella and Butyricimonas , is closely linked with increased intestinal permeability [79], a phenomenon often referred to as “leaky gut,” whereby compromised barrier integrity permits the translocation of microbe-associated molecular patterns (MAMPs) from the gut lumen into the lamina propria and potentially into systemic circulation [80,81,82,83]