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Available studies have shown that curcumin prevents chondrocyte apoptosis and inhibits the release of proteoglycans and metalloproteinases as well as the expression of cyclooxygenase, prostaglandin E-2, and inflammatory cytokines in chondrocytes (Yang et al., 2025)

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Open access publication fees were supported by the United States Department of Agriculture – Agricultural Research Service (USDA- ARS) grant 6040-42000-046-000D awarded to ReS