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However, studies showing that SnPP is a photosensitizer of bilirubin destruction in vitro (McDonagh and Palma, 1985), and phototoxic in vivo (Hintz et al., 1990) led to its abandonment for use in human infants

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The low anticancer activity is likely related to the relatively high stability of these metal complexes (Pettinari et al., 2021) (Figure 12)

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