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Also, pentadecapeptide BPC 157, given peripherally, could affect sphincter function through serotonin (51, 52) or dopamine (in the same dose-range that BPC 157 prevented/reversed catalepsy or stereotypy and all concomitant gastrointestinal lesions) (53-56), likely providing a particular balance between peripheral and central effects (57)

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Furthermore, we also found that approximately 50% of gad1b:mCherry neurons expressed Akt1 in the zebrafish midbrain by immunofluorescence staining (Fig