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Risk factors for inflammation associated with autism include maternal (odds ratio [OR] = 1.6, confidence interval [CI] 95% = 1.1–2.2) and perhaps paternal (OR = 1.4, CI 95% = 1.0–2.0) autoimmune diseases such as diabetes, myasthenia gravis, idiopathic thrombocytopenic purpura, or rheumatic fever, 1 maternal obesity (OR = 1.67, CI 95% = 1.1–2.56), 2 and febrile episodes during the first two trimesters (OR = 1.6, CI 95% = 1.0–2.5)
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