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The stress-induced increase in ATF4 leads to the expression of a canonical set of ATF4 target genes, including those involved in non-essential amino acid biosynthesis and amino acid transport, as part of the adaptive cellular response specific to stresses such as amino acid depletion (Harding et al., 2003)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 49.Katayama K., Yoshioka S., Tsukahara S., Mitsuhashi J., Sugimoto Y