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Illustratively, it is produced in the central nervous system (i.e., brainstem’s raphe nuclei) (1–2% of the serotonin in the human body), skin (i.e., Merkel cells), lung (pulmonary neuroendocrine cells), gastrointestinal tract (90% of the serotonin in the human body) (i.e., enterochromaffin cells), and rest of 8% is stored in platelets [166]

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Certain medical conditions, medications, or health factors may make peptide therapy inappropriate for some individuals