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The dose of lactulose (15 to 30ml administered 2 to 4 times a day) is titrated so that the patient has 3 to 5 bowel movements daily

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The enzymatic activities of Glutathione Peroxidase and Glutathione Reductase were determined with the following kits (from Cayman Chemical): Glutathione Peroxidase Assay Kit # 703102 and Glutathione Reductase Assay Kit# 703202, according to the manufacturer's instruction