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To further analyze the mechanism whereby glutamine treatment reduces reactivation of HSV in vivo, we performed RNA microarray experiments comparing gene expression of latently HSV-1–infected mouse trigeminal ganglia for animals treated with supplemental glutamine and those treated with glycine

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Although nonlinear dose–exposure relationships cannot be excluded for an endogenously regulated analyte, the higher exposure observed with LipoMicel ® relative to both a higher-dose standard formulation and a dose-matched liposomal formulation supports a formulation-dependent contribution to systemic glutathione delivery