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Cuproptosis is a copper-dependent form of cell death triggered by the direct binding of copper to lipoylated components of the TCA cycle, such as dihydrolipoamide S-acetyltransferase (DLAT), leading to mitochondrial proteotoxic stress, loss of iron–sulfur cluster proteins, and collapse of oxidative metabolism [120]

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An enzyme containing selenium that protects cells from oxidative damage