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Degeneration (“cupping” or “excavation”) of the ONH is the current diagnostic marker that separates glaucoma from other RGC diseases (e.g., nonarteritic anterior optic neuropathy (NAION), traumatic optic neuropathy, optic neuritis and multiple sclerosis)

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Interestingly, the clinical application of rivastigmine in ASD children significantly relieved overall ASD behaviors, however, several adverse effects including nausea, diarrhea, hyperactivity and irritability were reported (Hardan and Handen, 2002

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