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Further, it has been observed that ethanol is capable of indirect modulation of other neurotransmitters (dopamine, serotonin, opioid, and cholinergic), particularly in brain regions involved in the mesolimbic reward system [i.e., amygdala, hippocampus, striatum, and ventral tegmental area (VTA)] via GABAergic/glutamatergic neurons or their respective receptors present on other types of neurons (Abrahao et al., 2017)

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Novel lt N-degron for in vivo application Finally, we fused TTG1 to DHFR T39A/E173D ( K2 ), which only contains the two destabilizing point mutations T39A/E173D identified in the mutagenesis screen