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Additionally, participants were divided into low depression (score of 1 or 2 out of a possible score of four, as this is a core feature of MDD diagnosis) and high depression (score of 3 or greater out of a possible score of four)

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(2) depleted hepatic glutathione levels and its intermediates despite unchanged level of reactive oxygen species, suggesting glutathione consumption exceeds production due to systemic oxidative stress after AKI